Toxicological Evaluation of Biodiesel Emission Particles (BEP) Using Rat Models

Abstract
The present study is an attempt to elucidate the effect of biodiesel emission particles (BEP) on some antioxidant  enzymes of selected tissues of rats. Rats were exposed to emission particles (EP) of biodiesel blended with fuel  diesel at 100BD, 75BD, 50BD and 25BD as well as fuel diesel (FD) over a period of ten days. Enzyme assays  were conducted for superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX) and reduced  glutathione (GSH) in the liver, lungs, brain and serum of rats. Lungs CAT activity of Control is 229% higher than that of FD and789% that of 100BD. There existed no significant difference (p>0.05) in the brain CAT activity among all treatment groups. Serum CAT activity of Control group was significantly higher (p