STUDIES OF ALUMINIUM COMPLEXES OF SOME MODEL BIOLOGICAL LIGANDS

Complexes of Aluminium with some model bioligands, were prepared and characterized by elemental analysis, melting point, conductivity, solubility and infra-red spectroscopic studies. The complexes are soluble in water and some organic solvents such as chloroform, ethanol and methanol. The melting point ranges from 258°C - 282°C for complexes with Al Cl3, and 8Ql C - 95 C, for complexes with AlNH4(S04) 2 .12H2 0. Conductivity studies reveals that the prepared· complexes are non-electrolyte in water. The Infrared data reveals that Citrate, Succinate, Malonate and Glutarate, co-ordinate via the carboxylate group. Catechol coordinates via the oxygen atom. Guanine co-ordinates via the carbonyl oxygen, while coordination of glycine is through the carboxylate oxygen and amino nitrogen. Thus, catechol, Succinate, Guanine, malonate,glutarate, and glycine act as bidentate ligands while Citrate serves as tridentate ligand. The sulphate and chloride anions are coordinated to the metal in some of the complexes.