FERTILITY ENHANCING POTENTIAL AND METABOLIC EFFECT OF ETHANOLIC ROOT EXTRACT OF SPHENOCENTRUM JOLLYANUM IN MALE WISTAR RATS

The overall objective of this study is to scientifically evaluate the claimed fertility enhancing potential and to assess the metabolic effect of the ethanolic extract of  Sphenocentrum jollyanum pierre (Menispermaceae) root using male wistar rats as model.

The specific objectives include the following

·         To determine the proximate and phytochemical composition of the ethanolic extract of Sphenocentrum jollyanum  (root) this will justify the ethno pharmacological  use of the plant .

• ·       To evaluate the acute toxicity of the plant part and change in organ to body weight index of the male rats after administration of the extract.
• ·       To investigate the effect of the ethanolic extract of S. jollyanum root on semen and testicular morphology of male wistar rats . This will scientifically substantiate its efficacy and potency.
• ·          To assess the hematological parameters after administration of the extract. This will give information blood relating function of the plant extract .
• ·          To determine the effects of the plant extract on serum lipid profile, total protein and  albumin.
• ·         To investigate the duration (length of days) of optimal administration of the plant extract.
• ·         To provide information on the mode of action of the plant acclaimed fertility enhancing potential.