Comparative Physicochemical, Phytochemical And Acute Toxicity Studies Of Ocimum Gratissimum And Ocimum Suave Species In Western Uganda

ABSTRACT

Ocimum gratissimum and Ocimum suave belong to the family lamiaceae. Folkore medicine

claims their use in many conditions.

Leaves of 0 gratissimum and 0 suave were extracted in aqueous methanol by maceration,

extract was filtered and evaporated using the rotary evaporator and dried to a constant weight in

an oven. Phytochemical analysis was carried out to determine the active constituents and

Quantification tests were carried out to obtain the amount of phytochmicals in each extract.

Standard procedures were used to determine the physicochemical properties of the two leaves.

Acute toxicity studies were evaluated on laboratory rats, aiming at ascertaining the acute toxicity

profile of the two leaves extract. This research is expected to contribute to the knowledge of

acute toxicity of 0 gratissimum and 0 suave and their physicochemical and phytochemical

composition.