Characterization, Bioactivity And Qsar Studies Of Natural Products From Selected Namibian Red Marine Algae

ABSTRACT

The objective of this research was to discover new drug leads from Namibian marine algae. Plocamium extracts were screened and their phytochemical contents were quantified. Both the antioxidant activity and the antimicrobial activity of the crude extracts were determined, as well as the dose-response relationship for Plocamium extracts in BALB/c mice. This was done by using acute and sub-acute toxicity parameters. In addition, the structural elucidation of the major metabolite found in the crude extract was determined and the Quantitative Structure Activity Relationships (QSARs) of the compound were determined